Pack size
118 mL
Cost per litre treated
2.7c
Water type
Freshwater + Marine
Bottle treats
896 L
Dose rate
5 mL per 38 L weekly
Bacteria
Over 300 million per 5 mL
Consumes
Sludge, organic debris
Pack size
237 mL
Cost per litre treated
2.1c
Water type
Freshwater + Marine
Bottle treats
1801 L
Dose rate
5 mL per 38 L weekly
Bacteria
Over 300 million per 5 mL
Consumes
Sludge, organic debris
Pack size
473 mL
Cost per litre treated
1.7c
Water type
Freshwater + Marine
Bottle treats
3594 L
Dose rate
5 mL per 38 L weekly
Bacteria
Over 300 million per 5 mL
Consumes
Sludge, organic debris
Pack size
946 mL
Cost per litre treated
1.6c
Water type
Freshwater + Marine
Bottle treats
7189 L
Dose rate
5 mL per 38 L weekly
Bacteria
Over 300 million per 5 mL
Consumes
Sludge, organic debris
Pack size
30 mL
Cost per litre treated
2.3c
Water type
Freshwater + Marine
Bottle treats
228 L
Dose rate
5 mL per 38 L weekly
Bacteria
Over 300 million per 5 mL
Consumes
Sludge, organic debris
Pack size
1.89 L
Cost per litre treated
Under 1c
Water type
Freshwater + Marine
Bottle treats
14364 L
Dose rate
5 mL per 38 L weekly
Bacteria
Over 300 million per 5 mL
Consumes
Sludge, organic debris
Pack size
3.8 L
Cost per litre treated
Under 1c
Water type
Freshwater + Marine
Bottle treats
28880 L
Dose rate
5 mL per 38 L weekly
Bacteria
Over 300 million per 5 mL
Consumes
Sludge, organic debris
API Stress Zyme
Live bacteria that quietly consume sludge and waste. API Stress Zyme is a beneficial bacterial additive dosed weekly into freshwater and marine aquarium water, where it goes to work on organic build-up in gravel, decorations and filter media. It is sold across seven pack sizes, from a 30 mL trial bottle up to a 3.8 L bulk drum, so tanks of any scale can be dosed without waste.
Key features
- Contains over 300 million live bacteria per teaspoonful (5 mL), supplied in a dormant state that becomes active once added to aquarium water.
- Formulated to consume sludge and organic debris, helping keep gravel and glass cleaner and supporting the tank's existing biological filter.
- Suitable for both freshwater and marine (saltwater) aquariums, and can be dosed with fish already in the tank.
- Cost per litre of treated water, based on the standard weekly dose, ranges from around 2 cents per litre in the smaller bottles down to under 1 cent per litre in the 1.89 L and 3.8 L drums – this is a per-dose figure, not a one-off yield, since Stress Zyme is dosed repeatedly rather than used once.
Specifications
| Size | SKU | Water treated per weekly dose | Cost per litre (per dose) |
|---|---|---|---|
| 30 mL | BA1919 | 228 L | 2 cents/L |
| 118 mL | – | 896 L | 2 cents/L |
| 237 mL | – | 1,801 L | 2 cents/L |
| 473 mL | – | 3,594 L | 1 cent/L |
| 946 mL | – | 7,189 L | 1 cent/L |
| 1.89 L | BA1923 | 14,364 L | under 1 cent/L |
| 3.8 L | BA1971 | 28,880 L | under 1 cent/L |
Litres treated per dose are calculated from the manufacturer's stated rate of 5 mL per 10 US gallons (38 L), rounded down to the nearest whole litre. Water type, active bacteria count and shelf life are as published by API; bacterial strain names and a full ingredient list are not published by the manufacturer.
Dosage and directions
Shake well before use. Using the dosing cap, add Stress Zyme via the aquarium water surface.
- Established aquariums: add 5 mL (1 teaspoonful) per 10 US gallons (38 L) of water, once weekly.
- New aquariums: double the dose at start-up and continue for 2 additional weeks before reverting to the standard weekly rate.
Weekly dosing is intended to be ongoing for the life of the aquarium, not a single treatment – the litres-treated figures above describe one dosing round, not a total lifetime yield from the bottle.
Care and maintenance / storage
API states Stress Zyme has a 5-year shelf life and does not require refrigeration. Store the bottle upright, out of direct sunlight, and keep the cap tightened between doses. Specific manufacturer temperature limits for this exact formula are not published on the sources checked; as general practice, avoid storing any liquid aquarium additive somewhere it could freeze or overheat.
Suitable for / not suitable for
Suitable for freshwater and marine aquariums, both newly set up and established, and can be dosed while fish are present. It is a biological filtration aid, not a substitute for regular partial water changes, mechanical filter maintenance, or a treatment for fish disease – it should not be used as a medication.
Safety
API has not published a specific consumer hazard warning or first-aid statement for Stress Zyme on the sources checked. As with any aquarium additive, keep out of reach of children and pets, avoid contact with eyes, wash hands after handling, and dose only as directed on the label.
Goes well with
Pair with an API liquid or strip water test kit to monitor ammonia and nitrite while a new tank cycles, a dechlorinating water conditioner for use at water changes, and a gravel vacuum to physically remove the sludge the bacteria help break down.
Warranty and delivery
All API products sold by Nick's Aquarium Oceanarium Terrarium are covered by the consumer guarantees under the Australian Consumer Law.
Common questions
How often do I dose Stress Zyme?
Once weekly for established aquariums, at 5 mL per 10 US gallons (38 L) of water. New aquariums are dosed at double that rate for the first 2 weeks.
Can I use Stress Zyme with fish in the tank?
Yes, API's directions state it can be added while fish are in the aquarium.
Is Stress Zyme suitable for saltwater tanks?
Yes, it is labelled for use in both freshwater and marine aquariums.
Does Stress Zyme need to be refrigerated?
No. API states it has a 5-year shelf life and does not require refrigeration.
Which size should I buy?
Larger sizes carry a lower cost per litre of water treated per dose – the 1.89 L and 3.8 L drums work out to under 1 cent per litre, versus around 1-2 cents per litre from the smaller bottles – so regular users of larger tanks get better value from the bigger packs.
What exactly is in Stress Zyme?
API states each teaspoonful contains over 300 million live bacteria, supplied dormant and activated on contact with aquarium water. The manufacturer does not publish the specific bacterial strains or a full ingredient list.




